By Louis V. Avioli, Sook Won Lee (auth.), Shaul G. Massry, Eberhard Ritz, Henri Jahn (eds.)

We are happy to provide to our readers the lawsuits of the Fourth foreign Workshop on Phosphate and different Minerals which was once held in Strasbourg in the course of June 22-24, 1979. It was once hosted by way of Professor Henri Jahn, Professor of medication and leader, division of Nephrology on the collage of Strasbourg. those Workshops became a practice within the clinical scene of mineral metabolism. The conferences were supplying a distinct framework for shut interplay among scientists from a variety of disciplines, similar to nephrologists, endocrinologists, bio­ chemists, nutritionists, and people facing bone metabolism. The Workshops additionally created a discussion board for the supply of unique info, in addition to state of the art shows on fascinating issues of present curiosity during this evergrowing box of phosphate and mineral homeostasis. The Fourth foreign Workshop was once attended by means of 3­ hundred scientists from 15 nations together with Austria, Canada, Denmark, England, France, Germany, Holland, Israel, Italy, Japan, Sweden, Switzerland and the U.S. of the USA. the subjects mentioned integrated these facing the renal dealing with of phos­ phate, calcium and magnesium, middleman phosphate metabolism and phosphate homeostasis in healthiness and sickness. symposia have been additionally offered: one handled nephrolithiasis and its rela­ tion to phosphate and the opposite with bone metabolism. as well as 22 shows by means of invited audio system, the Workshop supplied forty six oral and ninety three poster displays chosen from over 250 abstracts submitted to the Organizing Committee.

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Phosphate and Minerals in Health and Disease

We're happy to offer to our readers the lawsuits of the Fourth overseas Workshop on Phosphate and different Minerals which was once held in Strasbourg in the course of June 22-24, 1979. It used to be hosted by way of Professor Henri Jahn, Professor of drugs and leader, division of Nephrology on the college of Strasbourg.

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1970, Effect of diuretics on urinary excretion of phosphate, calcium and magnesium in thyroparathyroidectomized dogs, J. Clin. , 76:257-266. Wong, N. , Quamme, G. A. and Dirks, J. , 1979, Contrasting effects of urea and mannitol on electrolyte transport in the dog nephron, Clin. , 27:434. Massry, S. , Ahumada, J. , Coburn, J. , and Kleeman, C. , 1970, Effect of MgC12 infusion on urinary Ca and Na during reduction in their filtered loads, Am. J. , 219:881-885. Coburn, J. , Massry, S. , and Kleeman, C.

T I ::I .. L • ~ ... L ~ 2 " WEEKS Fig 1. ) 100 i Urinary phosphate excretion expressed as ~Eq/day/100 g body weight during magnesium depletion in rats. From Smith et al (1). ,.... • • • ------: •••• ::E: S- 10 • ... Q) 0.. • ::E: ;::1. c;:t 0 0.. 5 0 I- 0 0 0 0 0 c'E'c:B 5 Fig 2. c Oe 20 10 15 Per ~1i n flM Fp04 Tubular phosphate reabsorption in non-parathyroidectomized control (I) and magnesium depleted (0) rats. Fpo4 denotes filtered load of phosphate and Tp04 indicates tubular reabsorption of phosphate.

Five different laboratories, including our own, have investigated calcium transport in this segment directly using the isolated rabbit renal tubule perfused in vitro by the method of Burg et al. 3 (Jr;) The unidirectional fluxes of calcium from lumen-to-bath and from bath-to-lumen (J£I) were measured in segments of TAL using 45Ca in the perfusate and in the bath respectively. Exhaustively dialyzed 3H-inulin was added to the perfusate as a volume marker. The tubules were perfused with a bicarbonate-free solution, and bathed with an artificial ultrafiltrate of rabbit serum with 5% by volume calf serum added.

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