By Institute of Medicine, Jr. John A. Benson, Jr. Stanley J. Watson, Janet E. Joy

The clinical use of marijuana is surrounded by means of a cloud of social, political, and spiritual controversy, which obscures the proof that are meant to be thought of within the debate. This publication summarizes what we all know approximately marijuana from evidence-based medication - the damage it might probably do and the relaxation it can carry to sufferers. The ebook is helping the reader comprehend not just what technology has to claim approximately scientific marijuana but additionally the common sense at the back of the clinical conclusions. ''Marijuana and Medicine'' addresses the technology base and the healing results of marijuana use for health conditions resembling glaucoma and a number of sclerosis. It covers marijuana's mechanism of motion, acute and protracted results on wellbeing and fitness and behaviour, power antagonistic results, efficacy of alternative supply structures, research of the knowledge approximately marijuana as a gateway drug, and the customers for constructing cannabinoid medications. The booklet evaluates how good marijuana meets permitted criteria for medication and considers the conclusions of different blue-ribbon panels. filled with valuable proof, this quantity can be very important to somebody drawn to proficient debate concerning the scientific use of marijuana: advocates and rivals in addition to policymakers, regulators, and healthiness care prone

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Additional info for Marijuana and Medicine: Assessing the Science Base

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This is a fraction with an unknown denominator. For the numerator we have a sample of positive responses; for the denominator we have no idea of the total number of people who have tried marijuana for medical purposes. Hence, it is impossible to estimate the clinical value of marijuana or cannabinoids in the general population based on anecdotal reports. Marijuana clearly seems to relieve some symptoms for some people—even if only as a placebo effect. But what is the balance of harmful and beneficial effects?

Animal studies typically provide information about how drugs work that would not be obtainable in clinical studies. At the same time, animal studies can never inform us completely about the full range of psychological and physiological effects of marijuana or cannabinoids on humans. The Active Constituents of Marijuana ∆9-THC and ∆8-THC are the only compounds in the marijuana plant that produce all the psychoactive effects of marijuana. Because ∆9-THC is much more abundant than ∆8-THC, the psychoactivity of marijuana has been attributed largely to the effects of ∆9-THC.

Ultimately, the complex moral and social judgments that underlie drug control policy must be made by the American people and their elected officials. A goal of this report is to 15 INTRODUCTION evaluate the biological and medical factors that should be taken into account in making those judgments. HOW THIS STUDY WAS CONDUCTED Information was gathered through scientific workshops, site visits, analysis of the relevant scientific literature, and extensive consultation with biomedical and social scientists.

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