By Herbert Weissbach

Dimensions In health and wellbeing study: look for The medications Of Tomorrow

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69, 3665 (1972). , Proc. Sei. 32. ) 70, Nat. Acad. 451 (1973). , and Lane, C D . , Proc. Nat. Acad. Sei. ) 69, 1606 (1972). 33. , in press. 34. , Lane, C D . , J. Molec. Biol. 61, 93 (1971). 35. , Lane, C D . , and Marbaix, 36. , Nature Proc. 37. Nat. (London) Acad. Sei. 233, 177 (1971). ) 69, 1203 (1972). , Biochem. Res. Commun. 59, Biophys. 1023 (1974). , and Friedmann. , J. Gen. Virol. 225 (1975). 39. , J. 38. Microbiol. 1, 116 (1975). 27, Clin. HUMAN INTERFERON 53 Discussion de Weck Pestka I would like to ask Dr.

All rights of reproduction in any form reserved. ISBN 0-12-744260-X 26 JOHN J. BURNS the pharmacologist are aware of what is going on, but it takes time. It takes time for the basic creations given to us by the molecular biologist on the subject of cellular processes to be fully understood. It takes time before these developments can be part of our every-day research, say, in terms of the development of new drugs. I think one thing I know from my experience in drug development over the past couple of decades is that there is no such thing as a short-term program in drug development.

Accordingly, it would not be surprising to discover relatively small peptides effectively simulating these regions and consequently interacting with the cell surface to generate potent antiviral activities. The Future Numerous possibilities exist for exploiting the clinical potential of the human interferons. Although it does not seem practical at present, cell cultures might provide sufficient human interferon if cells could be manipulated or new celllines found to produce larger amounts of the interferons than currently attainable.

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