Content:
Chapter 1 The Metabolism of C19 Steroids via person Tissues (pages 236–243): Leo T. Samuels
Chapter 2 In vivo Metabolism of C19 Steroids (pages 244–250): Frank Ungar and Ralph I. Dorfman
Chapter three Is Dehydroisoandrosterone remoted from Urine Extracts an unique 17?Ketosteroid or a made of Chemical Degradation? (pages 251–273): E. Dingemanse
Chapter four The impact of Androgens at the Urinary Excretion of Steroid Alcohols and ?strogens (pages 274–285): Lewis L. Engel, Marion Lance, Gladys Ekman, Katherine H. Spaulding, Priscilla Carter and Ira T. Nathanson
Chapter five Excretion of Steroids in a Case of Interstitial mobile Tumour of the Testis (pages 286–290): Eleanor H. Venning
Chapter 6 Metabolism of impartial C21 and C19 Steroids (pages 291–308): Ralph I. Dorfman
Chapter 7 Progesterone Metabolism—A evaluation (pages 309–326): William H. Pearlman
Chapter eight The Metabolism of Progesterone in Goats (pages 327–328): R. J. Boscott
Chapter nine The Separation of Urinary Cortical Steroids (pages 329–333): R. J. Boscott
Chapter 10 The middleman Metabolism of Progesterone in Human topics (pages 334–346): Ian F. Sommerville
Chapter eleven The Metabolism of Progesterone and similar Compounds (pages 347–353): Ralph I. Dorfman, Frank Ungar, Paul Wgnos, Robert M. Stecher and Norman Shumway
Chapter 12 Metabolic experiences on Orally Administered Progesterone (pages 354–358): Eleanor H. Venning
Chapter thirteen Blood Progesterone in being pregnant (pages 359–365): C. J. O. R. Morris
Chapter 14 On attainable Relationships among the Metabolic Breakdown of Progesterone and its organic task (pages 366–374): H. S. Guterman
Chapter 15 11?Oxygenating Enzyme process (pages 375–380): Ralph I. Dorfman and Mika Hayano
Chapter sixteen The Metabolism of Steroid Hormones in people (pages 381–417): okay. Dobriner and S. Lieberman
Chapter 17 The impression of Corticosteroids on Carbohydrate and Electrolyte Metabolism in vitro (pages 418–422): F. Verzar
Chapter 18 Chairman's last feedback (pages 423–424): R. ok. Callow

Show description

Read or Download Ciba Foundation Symposium - Metabolic Breakdown of Steroids (Book II on Colloquia on Endocrinology), Volume II PDF

Similar nonfiction_9 books

Trace Gas Exchange in Forest Ecosystems

This quantity summarizes the present wisdom at the alternate of hint gases among forests and the ambience with the limit that solely carbon and nitrogen compounds are incorporated. For this objective the quantity brings jointly and interconnects wisdom from varied disciplines of organic and atmospheric sciences.

Recoding: Expansion of Decoding Rules Enriches Gene Expression

The dynamic nature of interpreting the knowledge in messenger RNA was once unanticipated on the time the genetic code used to be first deciphered. We now understand that either the that means of person codons and the framing of the readout approach will be changed through details in particular messenger RNAs. This booklet describes this "Recoding" phenomenon, revealing the range of an extra layer of knowledge in mRNAs that serves to complement the expression of genes.

Observation of CP Violation in B± → DK± Decays

CP violation is a well-established phenomenon in particle physics, yet till 2001 it used to be merely saw in kaons. within the final decade, a number of matter-antimatter asymmetries were saw in impartial B mesons in response to the expectancies of the normal version of the susceptible interplay. Direct CP violation is usually anticipated within the decay charges of charged B+ mesons as opposed to that of B- mesons, notwithstanding the best results are found in a decay that happens simply two times in 10 million decays.

The Vascular Endothelium I

This quantity deals a accomplished evaluation of modern advances in study at the vascular endothelium. It presents a historic history and a advisor for destiny instructions in study. This e-book includes 20 chapters through a various staff of authors who've all made major contributions to the sector of analysis within the vascular endothelium.

Extra resources for Ciba Foundation Symposium - Metabolic Breakdown of Steroids (Book II on Colloquia on Endocrinology), Volume II

Example text

The figure shows the 17-ketosteroid pattern of a normal woman before and after administration of dehydroisoandrosterone acetate. Beside this we see the 17-ketosteroid pattern of a girl with an adrenal cortical adenoma. If the urine of the latter has been directly hydrolysed with hydrochloric acid, the amount of rdehydroisoandrosterone found would in fact have exceeded 150 mg. per 24 hr. Why, in spite of this, is the androsterone and aetiocholanolone content of such urine so extremely low? Mason’s conclusion was that there is a disturbance of 17-ketosteroid metabolism in such cases.

For this reason we heat the urine with benzene a t pH 7 (the other conditions being the same) before carrying out the acid hydrolysis. Not until this has been done do we add 1/10 vol. of conc. HC1 to the urine residue and extract further in the usual way. For the chromatographic analysis we took an aliquot of each of these two extracts, mixed them and proceeded in the usual way. The diagram then revealed a maximum I1 between maxima I and 111. However, when the extraction was done directly in acid medium in the ordinary way, this maximum I1 did not appear and the value for dehydroisoandrosterone was increased by an amount corresponding t o that of Compound I1 (Fig.

But this proved to be impossible; the compound was extracted only at higher temperatures. This led to the conclusion that i-androstanolone is in all probability present in combination, presumably esterified, in native urine. We did in fact succeed (once more by means of chromatographic analysis) in isolating i-androstanolone in the form of the sodium salt of its sulphate ester from the butanol extract. i-Androstanolone occurs in native urine in the form shown in Fig. 10. Heating of this ester in water or in alkaline solution is sufficient to cause partial saponification.

Download PDF sample

Rated 4.84 of 5 – based on 36 votes