A world staff of top investigators speak about fresh development of sensory buildings in decrease and better vertebrates. specialists in suitable fields--the phone cycle and mitogenic progress factors--present insightful contributions within the look for precursors and/or stem cells in each one experience organ plus the signs which keep watch over these precursors' differentiation either in general improvement and regeneration.


Show description

Read or Download Ciba Foundation Symposium 160 - Regeneration of Vertebrate Sensory Receptor Cells PDF

Best nonfiction_9 books

Trace Gas Exchange in Forest Ecosystems

This quantity summarizes the present wisdom at the trade of hint gases among forests and the ambience with the restrict that completely carbon and nitrogen compounds are incorporated. For this objective the amount brings jointly and interconnects wisdom from varied disciplines of organic and atmospheric sciences.

Recoding: Expansion of Decoding Rules Enriches Gene Expression

The dynamic nature of interpreting the data in messenger RNA used to be unanticipated on the time the genetic code was once first deciphered. We now understand that either the that means of person codons and the framing of the readout method should be transformed through info in particular messenger RNAs. This e-book describes this "Recoding" phenomenon, revealing the range of an extra layer of knowledge in mRNAs that serves to complement the expression of genes.

Observation of CP Violation in B± → DK± Decays

CP violation is a well-established phenomenon in particle physics, yet until eventually 2001 it was once simply saw in kaons. within the final decade, a number of matter-antimatter asymmetries were saw in impartial B mesons based on the expectancies of the normal version of the susceptible interplay. Direct CP violation can also be anticipated within the decay premiums of charged B+ mesons as opposed to that of B- mesons, although the best results are found in a decay that happens simply two times in 10 million decays.

The Vascular Endothelium I

This quantity bargains a entire assessment of contemporary advances in learn at the vascular endothelium. It offers a historic history and a consultant for destiny instructions in learn. This booklet includes 20 chapters by means of a various workforce of authors who've all made major contributions to the sphere of analysis within the vascular endothelium.

Additional resources for Ciba Foundation Symposium 160 - Regeneration of Vertebrate Sensory Receptor Cells

Sample text

From the pattern of tritiated thymidine labelling it can be seen that new supporting cells are generated along with the new hair cells. In the closely similar lateral line system, it has been shown directly that both the regenerated hair cells and the new supporting cells are daughters of supporting cells that have been roused to divide (Balak et a1 1990). The simplest interpretation of these phenomena postulates that the epithelium does indeed consist of only two cell types-the supporting cell and the hair cell.

Murgolis: What is the biochemical or molecular nature of the vertebrate Notch counterpart? Lewis: The Notch gene product, and its Xenopus counterpart (the Xotch gene product), are transmembrane proteins with homologies to epidermal growth factor (EGF), which itself is cleaved from a receptor-like transmembrane protein (Kidd et a1 1989, Johansen et a1 1989). There are experiments with transfected cells in culture showing that the Notch product can mediate cell-cell binding through an interaction with the product of another related gene called Delta (Fehon et a1 1990).

Burd: What is the expression of Notch in the adult fly? For instance, can Notch be operating to prevent differentiation at certain times in the adult? Lewis: I don’t know. In Drosophiiu there is no epidermal cell division once the adult state has been reached, so everything is static, and the maintenance of those controls may become unnecessary. But in holometabolousinsects, which go through repeated moults, like Rhodniusprolixus, new bristles are generated at each moult in a way that reflects the rules I described (Wigglesworth 1940, Simpson 1990).

Download PDF sample

Rated 4.96 of 5 – based on 3 votes