By Henry Gautier (auth.), Jean-Marc Pequignot, Constancio Gonzalez, Colin A. Nurse, Nanduri R. Prabhakar, Yvette Dalmaz (eds.)

Since 1959, the foreign Society of Arterial Chemoreception (ISAC) has prepared in numerous nations fifteen clinical conferences dedicated to the mechanisms of peripheral arterial chemoreception and chemoreceptor reflexes. After the assembly held in Philadelphia with Sukhamay Lahiri as president, ISAC club elected Lyon (CNRS, college Claude Bernard, France) because the website of the xv" ISAC Symposium. The Symposium used to be successfully held in Lyon from the 18th to the twenty second of November 2002 and Jean-Marc Pequignot was once its president. The organizers have been Jean-Marc Pequignot and Yvette Dalmaz Lyon (CNRS, college Claude Bernard, France) and the medical Committee used to be shaped by means of John Carroll (University of Arkansas for scientific Sciences, USA), Constancio Gonzalez (University of Valladolid, Spain), Prem Kumar (University of Birmingham, U. ok. ), Sukhamay Lahiri (University of Pennsylvania, Philadelphia, USA), Colin Nurse (McMaster collage, Hamilton, Ontario, Canada), and Nanduri Prabhakar (Case Western collage, Cleveland, Ohio, USA). The Symposium in Lyon meant to stick to the trail opened in Philadelphia collecting humans operating on the interface of mobile and molecular biology with researchers within the extra classical themes of chemoreception pathways and reflexes. the purpose used to be to affix specialists with varied views. alongside those traces, a few individuals are engaged within the exploration of the intimate mechanisms of oxygen sensing and mobile responses, with their paintings founded in quite a few arrangements masking a large spectrum from micro organism, to chemoreceptor cells or to valuable fearful platforms neurons.

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2001). , 2000). TASK-2 activation is time-dependent with a time constant of about 60 ms at 0 mY. , 1998). , 2000). , 2000). , 2000). Unlike TASK-I, TASK-2 is also stimulated by chloroform. , 2000). , 2000). 6. , 2000). , 2001). , 2001). , 2000). , 2000). , 2000). , 2000) . , 2000). , 2001). , 2001). TALK-1 and TALK-2 are background K+currents which are activated by alkaline pH, but are insensitive to arachidonic acid. , 2001). , 2001). 7. CONCLUSIONS AND PERSPECTIVES These recent findings provide strong evidence that 2P domain K+ channels are sensitive molecular targets for volatile anesthetics.

Chem . 275: 16969-16978. , Zilberberg, N. , 2001, Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers. 1. Bioi. Chem 276: 2444924452. P. , 1998, Actions of general anaesthetics and arachidonic acid pathway inhibitors on K+ currents activated by volatile anaesthetics and FMRFamide in molluscan neurones. Br. 1. Pharmacol. 125: 309-318. , 1996, Oxygen-sensing by ion channels and the regulation of cellular functions. Trends Neurosci. 19: 435-40. B. , 1991, Anesthetic effects on resting membrane potential are voltage-dependent and agent-specific.

C. (2000). Viral gene transfer of dominant-negative Kv4 construct suppresses an O 2- sensitive K+ current in chemoreceptor cells. J Neurosci 20:5689-5695. Rudy, B. and McBain, C. J. (2001). Kv3 channels: voltage-gated K+ channels designed for highfrequency repetitive firing. Trends Neurosci 24:517-526. , Lopez-Lopez, J. , Perez-Garcia, M. , Ganfomina, M. , and Gonzalez, C. (2002). Molecular identification of Kvalpha subunits that contribute to the oxygen-sensitive K+ current of chemoreceptor cells of the rabbit carotid body.

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