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19 inhibitor on morphine analgesia, tolerance and physical dependence. J. Pharmacol, exp. Ther. 190:165-175 (1974). S. and Swanson, L. : Physical dependence on and tolerance to alcohol in the rat. Physiol. Behav. 6:191-198 (1971). A. : Tremor detec­ tor for the mouse. J. Appl. Physiol. 26:640-643 (1969). W. : Tremor analyzer for small laboratory animals. J. appl. Physiol. 25:513-514 (1970). : Animal models of ethanol withdrawal syndromes and their relevance to pharmacology, Biological and Be­ havioral Approaches to Drug Dependence.

M. : Comparison of various ETHANOL DEPENDENCE 39 methods for the determination of γ-aminobutyric acid and other amino acids in rat brain with reference to ethanol intoxication. J. Neurochem. 10:489-494 (1963). Sutton, I. and Simmonds, M. : Effects of acute and chronic ethanol on the γ-aminobutyric acid system in rat brain. Biochem. Pharm. 22:1685-1692 (1973). Sytinsky, I. , Guzikov, B. , Gomanko, M. , Eremin, V. P. and Konovalova, N. : The gamma-aminobutyric acid (GABA) system in brain during acute and chronic ethanol intoxication.

Biochem. Pharmacol. 15:711-721 (1966). Videla, L. : Factors that modify the metabolism of ethanol in rat liver and adaptive changes produced by its chronic administration. Biochem. J. 110:275-281 (1970). Pohorecky, L. : Effects of ethanol on central and brain and heart. Acta. 34. 6 A:97- 109 (1968). Aghajanian, G. , Graham, A. W. and Sheard, M. : Serotonin-containing neurons in brain: Depression of firing by MAO inhibitors. Science 169:1100-1102 (1970). Hunt, W. A. : Alterations in the turnover of brain norepinephrine and dopamine in alcohol-dependent rats.

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